Preservative and Additive Analysis
AAL's cosmetics scientists can analyze most of the additives (color, artificial sweetener, etc.) and preservative ingredients listed by USP monograph and FDA Cosmetics Handbook. Computerized automated HPLC and GC perform all chemical testing.
Chemical analysis is conducted under GMP requirements and complies with USP Chromatography system suitability requirements.
Preservative Testing |
Additive Testing |
Active purity content |
Color additives FD&C red, yellow, blue, green |
Preservative efficacy or microbial 30-day challenges |
Formaldehyde content |
Below is a list of the approved preservatives, color additives, and sweetener additives commonly used in cosmetics:
Partial List of the Approved Preservatives (USP/NF grade)
Commonly Used in Cosmetics:
Method |
||
Butyl Parabens |
0.05-0.1% |
HPLC |
Diazolidinyl Urea |
0.1-0.3% |
HPLC |
DMDM Hydantoin |
0.2-0.6% |
HPLC |
Ethyl Paraben |
0.8-0.1% |
HPLC |
Imidazolidnyl Urea |
0.1-0.5% |
HPLC |
Isobutyl Paraben Sodium Methyl Paraben |
0.05-0.2% |
HPLC |
Kathon cG (Methylchloroisothiazolone, and Methyllisothiazolone) |
max 0.1% |
HPLC |
Methyl Paraben |
0.1-0.3% |
HPLC |
Methylisothiazolinone |
max 0.02% |
HPLC |
Phenoxy ethanol |
0.3-0.5% |
HPLC |
Propyl Paraben |
0.01-0.1%> |
HPLC |
Quaternium-15 (dowicil 200) |
max 0.2% |
Redox - Titration |
Sodium Benzoate |
HPLC |
|
Tricarnilide |
HPLC |
|
Triclosan |
.0.1-0.4% |
HPLC |
Sweetener Additives:
Method |
|
Acesulfame |
HPLC |
Aspartame |
HPLC |
Mannitol |
HPLC / IC |
Saccharin |
HPLC |
Sorbitol |
HPLC / IC |
Xylitol |
HPLC / IC |